Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.4
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%

Top Medical Research Studies

8
Magnesium improves chest pain outcomes
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Read More
8
Magnesium shows promise for angina
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.

While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
Read More
8
Magnesium supplementation aids chest pain
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More

Most Useful Reviews

9
Reduced chest pain
44 people found this helpful
I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.
Read More
9
Alleviated back pain
17 people found this helpful
I started taking magnesium for my back pain, and within a few days, I noticed significant relief. The pain almost disappeared, but it returns if I forget to take it!
Read More
0
Relieved chest tingling
3 people found this helpful
I experienced chest tingling, lack of sleep, and heart palpitations. After taking this product, I am grateful as my symptoms have improved significantly.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
  • All Researches
9.5
Magnesium's unclear role in chest pain
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.

Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.

While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Read More
8
Magnesium supplementation aids chest pain
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More
8
Potassium magnesium aspartate improves chest pain
We explored how potassium magnesium aspartate could offer protective benefits against chest pain linked to coronary artery disease. In a study involving 98 patients with angina and arrhythmia, participants were divided into two groups. One group received the routine treatment for heart disease along with potassium magnesium aspartate, while the other only received the standard therapy.

After a week of treatment, we examined various markers of oxidative stress and monitored cardiac rhythms. The results were promising: potassium magnesium aspartate significantly improved oxidative stress levels and reduced lipid oxidative damage in patients. Notably, there was a marked decrease in the frequency of premature heartbeats in those receiving potassium magnesium aspartate compared to the control group.

It appears that by enhancing oxidative stress status, potassium magnesium aspartate may also contribute to alleviating symptoms associated with arrhythmia, including chest pain. This suggests that oxidative stress could play a critical role in the development of arrhythmias, and addressing it might help treat related symptoms effectively.
Read More
8
Magnesium benefits CAD patients
In a controlled study involving 53 male patients with stable coronary artery disease (CAD), we investigated the impact of oral magnesium supplementation on exercise-related heart rate and chest pain. Some participants received 15 mmol of magnesium twice daily, while others were given a placebo for six months.

Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.

By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
Read More
8
Magnesium improves chest pain outcomes
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 13 Reviews
7.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced chest pain
44 people found this helpful
I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.
Read More
9
Alleviated back pain
17 people found this helpful
I started taking magnesium for my back pain, and within a few days, I noticed significant relief. The pain almost disappeared, but it returns if I forget to take it!
Read More
0
Relieved chest tingling
3 people found this helpful
I experienced chest tingling, lack of sleep, and heart palpitations. After taking this product, I am grateful as my symptoms have improved significantly.
Read More
9
Diminished chest pain
1 people found this helpful
I purchased this after experiencing heart pain, and I've noticed a benefit. After about two weeks, my pain decreased by 90%. I continue using it as it enhances sleep and regulates muscle and joint function. Magnesium is essential for our bodies.
Read More
9
Eliminated chest pain
8 people found this helpful
After my first use, I experienced relief from heart pain, lower back pain, and constipation. I couldn't believe the results, especially since I had suffered for a long time. I decided to try this product after getting the Corona vaccine and watching supportive videos about magnesium.
Read More

Frequently Asked Questions

9
Diminished chest pain
1 people found this helpful
I purchased this after experiencing heart pain, and I've noticed a benefit. After about two weeks, my pain decreased by 90%. I continue using it as it enhances sleep and regulates muscle and joint function. Magnesium is essential for our bodies.
9
Eliminated chest pain
8 people found this helpful
After my first use, I experienced relief from heart pain, lower back pain, and constipation. I couldn't believe the results, especially since I had suffered for a long time. I decided to try this product after getting the Corona vaccine and watching supportive videos about magnesium.
9
Alleviated back pain
17 people found this helpful
I started taking magnesium for my back pain, and within a few days, I noticed significant relief. The pain almost disappeared, but it returns if I forget to take it!
0
Caused stomach issues
2 people found this helpful
Unfortunately, I ordered this magnesium after my usual brand was out of stock due to positive reviews. However, it caused stomach pain and diarrhoea after four days of use. The only plus point was that it was easy to swallow.
9
Reduced chest pain
44 people found this helpful
I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.
0
Unhelpful for cramps
2 people found this helpful
This magnesium is the least effective form, oxide. It caused severe diarrhoea, and I did not find it helpful for cramps due to magnesium deficiency. After experiencing abdominal pain, I stopped taking it.
0
Relieved chest tingling
3 people found this helpful
I experienced chest tingling, lack of sleep, and heart palpitations. After taking this product, I am grateful as my symptoms have improved significantly.
0
Stomach pain only
1 people found this helpful
I took one tablet daily, but it caused abdominal pain and diarrhoea. It may be more beneficial for those suffering from constipation.
8
Magnesium supplementation aids chest pain
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
7
Magnesium treatment ineffective for chest pain
We explored the effects of magnesium treatment on individuals experiencing chest pain, particularly considering its role in preventing serious heart conditions. The study carefully evaluated how magnesium might mitigate the discomfort linked to coronary issues, providing a focused observation of its immediate impact on chest pain symptoms.

Throughout the research, we aimed to determine whether magnesium could offer a significant relief to patients. Our findings, however, revealed that while magnesium has various health benefits, it did not show a significant effect on alleviating chest pain in the observed population.

Despite its widely recognized benefits in other contexts, we concluded that magnesium treatment might not be the solution for chest pain relief that many have hoped for. More research is required to better understand how we might effectively treat chest pain in various patients.
8
Magnesium reduces chest pain severity
We investigated whether magnesium could prevent coronary spasm in patients with vasospastic angina. In our trial, 22 patients received magnesium sulfate after experiencing a coronary spasm induced by acetylcholine. The results showed that magnesium infusion not only dilated the coronary arteries but also significantly reduced chest pain severity in 71% of the patients.

In contrast, the control group given isotonic glucose did not experience any improvement. Overall, magnesium appears promising in mitigating chest pain linked to coronary spasms.
8
Magnesium shows promise for angina
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.

While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
We examined the effects of magnesium on patients with suspected acute myocardial infarction using a double-blind, placebo-controlled approach involving 298 participants. Half received intravenous magnesium, while the other half received a placebo.

Despite increased serum magnesium levels, we found no significant impact on in-hospital or long-term mortality rates between the two groups. Notably, the magnesium group experienced a higher incidence of heart rhythm issues. Overall, our findings indicate that magnesium does not provide meaningful benefits for treating acute ischemic heart syndromes.

References

  1. Ola O, Gharacholou SM, Del-Carpio Munoz F. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021;181:1393. 10.1001/jamainternmed.2021.4021
  2. Poudel A. An adolescent with tingling and numbness of hand: gitelman syndrome. N Am J Med Sci. 2015;7:27. 10.4103/1947-2714.150086
  3. Amoozgar H, Rafizadeh H, Ajami G, Borzoee M. The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy. Int Cardiovasc Res J. 2012;6:92.
  4. Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
  5. Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006;40:773.
  6. Sovová E, Skvarilová M, Bartousek J, Doupal V, Lukl J, et al. [Latent tetany in patients with a negative coronarographic finding]. Vnitr Lek. 1999;45:291.
  7. Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
  8. Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.
  9. Ezhov AV, Pimenov LT. [Effect of adjuvant magnesium therapy on the quality of life and emotional status of elderly patients with stable angina]. Adv Gerontol. 2002;10:95.
  10. Teragawa H, Kato M, Yamagata T, Matsuura H, Kajiyama G. The preventive effect of magnesium on coronary spasm in patients with vasospastic angina. Chest. 2000;118:1690.
  11. Sueda S, Saeki H, Otani T, Mineoi K, Kondo T, et al. Limited efficacy of magnesium for the treatment of variant angina. J Cardiol. 1999;34:139.
  12. Shibata M, Ueshima K, Harada M, Nakamura M, Hiramori K, et al. Effect of magnesium sulfate pretreatment and significance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infarction. Angiology. 1999;50:573.
  13. Redwood SR, Bashir Y, Huang J, Leatham EW, Kaski JC, et al. Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study. Eur Heart J. 1997;18:1269.
  14. Satake K, Lee JD, Shimizu H, Ueda T, Nakamura T. Relation between severity of magnesium deficiency and frequency of anginal attacks in men with variant angina. J Am Coll Cardiol. 1996;28:897.
  15. Gawaz M, Reininger A, Neumann FJ. Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium. Thromb Res. 1996;83:341.
  16. Otani H, Kawasaki H, Ninomiya H, Kido M, Kawaguchi H. [Significance of hot shot in patients with unstable angina undergoing emergency coronary artery bypass graft surgery]. Nihon Kyobu Geka Gakkai Zasshi. 1996;44:123.
  17. Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg. 1995;59:942.
  18. Feldstedt M, Boesgaard S, Bouchelouche P, Svenningsen A, Brooks L, et al. Magnesium substitution in acute ischaemic heart syndromes. Eur Heart J. 1991;12:1215.
  19. Tanabe K, Noda K, Mikawa T, Murayama M, Sugai J. Magnesium content of erythrocytes in patients with vasospastic angina. Cardiovasc Drugs Ther. 1991;5:677.
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